UNDERSTANDING INJECTIONS

At home or on the go, learn what’s right for you.

It’s important to know how and where to inject. For injection training assistance, rely on downloadable resources or schedule an appointment with your healthcare provider.

Starting COPAXONE^®

Switching to COPAXONE^® 40 mg

GETTING COMFORTABLE WITH INJECTIONS

COPAXONE^® comes in a prefilled syringe with needle attached. How often a dose is given depends on the product strength that is prescribed. Your doctor will prescribe the correct dose for you.

Prefilled syringe used for
administration and usage of
COPAXONE®.

For subcutaneous injection only. Do not inject COPAXONE in your veins (intravenously). Do not re-use your COPAXONE prefilled syringe. Do not share your COPAXONE prefilled syringe with another person.¹

Ready for fewer injections?

Ask your doctor about 3-times-a-week COPAXONE^® 40 mg.

An image of the autoject®2 for glass syringe used for administration and usage of COPAXONE®.

With 3-times-a-week COPAXONE^® 40 mg, you’re in control of your MS therapy ROUTINE.¹

Choose a consistent (approximately the same time and on the same days each week) 3-times-a-week schedule that works wherever—and whenever— for you (example: Monday, Wednesday, and Friday); injections must be at least 48 hours apart.¹

Watch our COPAXONE^® injection video for step-by-step instructions:

Wherever you are in your therapy experience, training matters.

Even if you have used an injectable therapy before, you should be trained by a doctor or nurse before injecting COPAXONE^® for the first time.

Injection Tips

Injection Training

IMPORTANT SAFETY INFORMATION

Serious allergic reactions (anaphylactic reactions) that may be life-threatening or lead to death may happen any time after you start using COPAXONE. These reactions may happen right after your first dose up to years after starting treatment with COPAXONE, even if you never had an allergic reaction before. Many reactions have happened within 1 hour of using COPAXONE. Some signs and symptoms may be the same as those of an immediate post-injection reaction. See What are the possible side effects of COPAXONE?

What is COPAXONE?

COPAXONE is a prescription medicine that is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

It is not known if COPAXONE is safe and effective in children under 18 years of age.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about COPAXONE?

Serious allergic reactions (anaphylactic reactions). Serious allergic reactions that may be life-threatening or lead to death may happen any time after you start using COPAXONE. These reactions may happen right after your first dose up to years after starting treatment with COPAXONE, even if you never had an allergic reaction before. Many reactions have happened within 1 hour of using COPAXONE. Some signs and symptoms may be the same as those of an immediate post-injection reaction. See What are the possible side effects of COPAXONE?

Stop using COPAXONE and get emergency help right away if you have:
- widespread rash
- swelling of the face, eyelids, lips, mouth, throat, or tongue
- sudden shortness of breath, difficulty breathing, or wheezing
- uncontrolled shaking (convulsions)
- trouble swallowing or speaking
- fainting, feeling dizzy or faint

Do not take COPAXONE:

if you are allergic to glatiramer acetate or mannitol. Serious allergic reactions including life-threatening or anaphylactic reactions that can lead to death have happened.

What should I tell my healthcare provider before taking COPAXONE?

Before you use COPAXONE, tell your healthcare provider about all of your medical conditions, including if you:

are pregnant or plan to become pregnant. Talk to your healthcare provider who will advise if you should take COPAXONE during your pregnancy.
are breastfeeding or plan to breastfeed. It is not known if COPAXONE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while using COPAXONE.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

COPAXONE may affect the way other medicines work, and other medicines may affect how COPAXONE works.

Know the medicines you take. Keep a list of your medicines with you to show your healthcare provider and pharmacist when you get a new medicine.

What are the possible side effects of COPAXONE?

COPAXONE may cause serious side effects, including:

Immediate Post-Injection Reactions. Serious side effects may happen right after or within minutes after you inject COPAXONE at any time during your course of treatment. Some signs and symptoms may be the same as those of a serious allergic reaction (anaphylaxis). See What is the most important information I should know about COPAXONE? Call a healthcare provider right away if you have any of these immediate post-injection reaction symptoms including:
- redness to your cheeks or other
  parts of the body (flushing)
- chest pain
- fast heartbeat
- anxiety
- breathing problems or tightness in your throat
- swelling, rash, hives, or itching

If you have symptoms of an immediate post-injection reaction, do not give yourself more injections until a healthcare provider tells you to.

Chest Pain. You can have chest pain as part of an immediate post-injection reaction or by itself. This type of chest pain usually lasts a few minutes and can begin around 1 month after you start using COPAXONE. Call your healthcare provider right away if you have chest pain while using COPAXONE.
Damage to your skin. Damage to the fatty tissue just under your skin’s surface (lipoatrophy) and, rarely, death of your skin tissue (necrosis) can happen when you use COPAXONE. Damage to the fatty tissue under your skin can cause a “dent” at the injection site that may not go away. You can reduce your chance of developing these problems by:
- following your healthcare provider’s instructions for how to use COPAXONE
- choosing a different injection area each time you use COPAXONE.
Liver problems. Liver problems, including liver failure, can occur with COPAXONE. Call your healthcare provider right away if you have symptoms, such as:
- nausea
- loss of appetite
- tiredness
- dark colored urine and pale stools
- yellowing of your skin or the white part of your eye
- bleeding more easily than normal
- confusion
- sleepiness

The most common side effects of COPAXONE are:

skin problems at your injection site, including:
- redness
- pain
- swelling
- lumps
- itching
rash
shortness of breath
flushing (vasodilation)
chest pain

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of COPAXONE. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the accompanying Medication Guide.

Reference:

COPAXONE^® (glatiramer acetate injection) Current Prescribing Information Parsippany, NJ. Teva Neuroscience, Inc.

Injections for 3-times-a-week COPAXONE^® 40 mg must be at least 48 hours apart.

UNDERSTANDING INJECTIONS

Starting COPAXONE®

Switching to COPAXONE® 40 mg

Watch our COPAXONE® injection video for step-by-step instructions:

Wherever you are in your therapy experience, training matters.

Starting COPAXONE^®

Switching to COPAXONE^® 40 mg

Watch our COPAXONE^® injection video for step-by-step instructions: