HERE TO ANSWER QUESTIONS ABOUT INJECTING.

We’ve put information you need to know about how to inject COPAXONE® in one convenient place, with easy-to-reference tips on storage, disposal and travel too.


Watch our COPAXONE® injection video for step-by-step instructions:

How to inject COPAXONE®:

Whether you are starting injections for the first time with your COPAXONE® prescription, or switching to COPAXONE® from another therapy:

  1. 1

    Ready to begin? Take the COPAXONE® pre-filled syringe out of the refrigerator at least 20 minutes before you inject.1 Injecting when COPAXONE® is at room temperature can help avoid discomfort.

  2. 2

    Apply a warm compress to the injection site (with a cloth barrier between the warm compress and bare skin) for 5 minutes to help relax the tissue before cleaning the site and injecting.

  3. 3

    Next, follow proper injection technique. See video above, or refer to the full Prescribing Information.

  4. 4

    After the injection, use a cold pack (with a cloth barrier between the cold pack and bare skin) on the injection site for up to 1 minute.

While the injection experience is different for everyone, and you should always follow your doctor’s recommendations, rotating injection sites is important to help keep your skin healthy and reduce your risk of injection site reactions.1 Download the COPAXONE iTracker® 2.0 app to track your injections at any time.

Finding the right autoject®2 for glass syringe depth setting:

The right depth setting for each injection area can help make injections more comfortable. Changes in weight, size, and differences in areas of your body all impact your depth settings, so it’s important to speak with your doctor to determine what’s best for your injections. Using depth settings that are too deep or too shallow may contribute to injection site reactions.

Recommended depth settings
Amount of "fatty" tissueautoject®2 for glass syringe

Pinch less than 1 inch
(lean or muscular part of the body)

4-5

Pinch 1 inch

6

Pinch 2 inches

8

Pinch >2 inches

10

Important tips for injecting with the autoject®2 for glass syringe:

  • DO NOT pinch up the skin.

  • Use only light pressure with the autoject®2 for glass syringe—just enough to release the safety mechanism. If you notice a red ring imprint on your skin after you remove the autoject®2 for glass syringe, you may be using more pressure than you need.

  • If you are injecting in an area that you have used in the last 7 days, be sure to choose a site that is at least 2 inches away from the site where you last injected.

  • If your autoject®2 for glass syringe is older than 3 years or has been used for more than 1,000 injections, call Teva’s Shared Solutions® at 1-800-887-8100 for a replacement (free with your prescription).

  • Always keep out of reach of children.

How do I store COPAXONE®?1

Keep your supply of COPAXONE® pre-filled syringes refrigerated and protected from light when not injecting. The ideal storage temperature is between 36°F and 46°F (2°C-8°C). Avoid leaving your COPAXONE® in a hot or cold car.

When traveling with COPAXONE® or when you are not able to refrigerate, pre-filled syringes may be stored at room temperature between 59°F and 86°F (15°C-30°C), for up to 1 month. Discard after one month.

What happens if COPAXONE® freezes?1

Never freeze your COPAXONE® pre-filled syringes. If they do accidentally freeze, do not use, and dispose of your COPAXONE® in a proper container.

How do I dispose of COPAXONE® Pre-filled syringes?1

Remember to properly dispose of used syringes into a hard-walled container immediately after you inject for safe needle disposal. Consider using a needle clip device, available online and at many retail pharmacies, which snaps your used needle off the syringe and houses it in a small device that can hold hundreds of needles before requiring disposal. Check with your local health department, doctor's office, or pharmacist for guidance on how to follow local biohazard regulations for disposing of the needle clip device. Always keep your waste container in an area of your home that is out of the reach of children and pets.

COPAXONE® disposal of pre-filled syringes

How do I manage traveling with COPAXONE®?

For your free COPAXONE® Travel Kit, call Teva’s Shared Solutions® at 1-800-887-8100. Get started by downloading our Travel Planning Guide.

Packing

Stay prepared for unexpected changes in plans by keeping extra supplies on hand, including syringes, cotton balls and alcohol wipes, protected in sealed plastic bags. Avoid unnecessary delays by bringing your current prescription label with you; the label should match your name as it appears on your government-issued ID.

Flying

Keep your COPAXONE® pre-filled syringes and autoject®2 for glass syringe in your carry-on luggage, so they're easily available when going through airport security and safely in your possession if your luggage gets lost or damaged. Rest assured, your COPAXONE® should not be affected when passing through X-ray security measures at the airport. For current regulations, contact the Transportation Security Administration.

Use

COPAXONE® is a prescription medicine that is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Important Safety Information

Do not use COPAXONE® if you are allergic to glatiramer acetate or mannitol.

Serious side effects may happen right after or within minutes after you inject COPAXONE® at any time during your course of treatment. Call your doctor right away if you have any of these immediate post-injection reaction symptoms including: redness to your cheeks or other parts of the body (flushing); chest pain; fast heart beat; anxiety; breathing problems or tightness in your throat; or swelling, rash, hives, or itching. If you have symptoms of an immediate post-injection reaction, do not give yourself more injections until a doctor tells you to.

You can have chest pain as part of an immediate post-injection reaction or by itself. This type of chest pain usually lasts a few minutes and can begin around 1 month after you start using COPAXONE®. Call your doctor right away if you have chest pain while using COPAXONE®.

Damage to the fatty tissue just under your skin’s surface (lipoatrophy) and, rarely, death of your skin tissue (necrosis) can happen when you use COPAXONE®. Damage to the fatty tissue under your skin can cause a “dent” at the injection site that may not go away. You can reduce your chance of developing these problems by following your doctor’s instructions for how to use COPAXONE® and choosing a different injection area each time you use COPAXONE®.

The most common side effects of COPAXONE® include redness, pain, swelling, itching, or a lump at the injection site; rash; shortness of breath; flushing; and chest pain.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of COPAXONE®. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the Patient Information in the full Prescribing Information.

Reference: 1. COPAXONE® (glatiramer acetate injection) Current Prescribing Information. Teva Neuroscience, Inc.

Injections for 3-times-a-week COPAXONE® 40 mg must be at least 48 hours apart.

autoject®2 for glass syringe is a registered trademark of Owen Mumford, Ltd. Available by prescription only.
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