HERE TO ANSWER QUESTIONS ABOUT INJECTING.

We’ve put information you need to know about how to inject COPAXONE® in one convenient place, with easy-to-reference tips on storage, disposal and travel too.


Watch our COPAXONE® injection video for step-by-step instructions:

How to inject COPAXONE®:

Whether you are starting injections for the first time with your COPAXONE® prescription, or switching to COPAXONE® from another therapy:

  1. 1

    Ready to begin? Take the COPAXONE® pre-filled syringe out of the refrigerator at least 20 minutes before you inject.1 Injecting when COPAXONE® is at room temperature can help avoid discomfort.

  2. 2

    Apply a warm compress to the injection site (with a cloth barrier between the warm compress and bare skin) for 5 minutes to help relax the tissue before cleaning the site and injecting.

  3. 3

    Next, follow proper injection technique. See video above, or refer to the full Prescribing Information.

  4. 4

    After the injection, use a cold pack (with a cloth barrier between the cold pack and bare skin) on the injection site for up to 1 minute.

While the injection experience is different for everyone, and you should always follow your doctor’s recommendations, rotating injection sites is important to help keep your skin healthy and reduce your risk of injection site reactions.1 Download the COPAXONE iTracker® 2.0 app to track your injections at any time.

Finding the right autoject®2 for glass syringe depth setting:

The right depth setting for each injection area can help make injections more comfortable. Changes in weight, size, and differences in areas of your body all impact your depth settings, so it’s important to speak with your doctor to determine what’s best for your injections. Using depth settings that are too deep or too shallow may contribute to injection site reactions.

Recommended depth settings
Amount of "fatty" tissueautoject®2 for glass syringe

Pinch less than 1 inch
(lean or muscular part of the body)

4-5

Pinch 1 inch

6

Pinch 2 inches

8

Pinch >2 inches

10

Important tips for injecting with the autoject®2 for glass syringe:

  • DO NOT pinch up the skin.

  • Use only light pressure with the autoject®2 for glass syringe—just enough to release the safety mechanism. If you notice a red ring imprint on your skin after you remove the autoject®2 for glass syringe, you may be using more pressure than you need.

  • If you are injecting in an area that you have used in the last 7 days, be sure to choose a site that is at least 2 inches away from the site where you last injected.

  • If your autoject®2 for glass syringe is older than 3 years or has been used for more than 1,000 injections, call Teva’s Shared Solutions® at 1-800-887-8100 for a replacement (free with your prescription).

  • Always keep out of reach of children.

How do I store COPAXONE®?1

Keep your supply of COPAXONE® pre-filled syringes refrigerated and protected from light when not injecting. The ideal storage temperature is between 36°F and 46°F (2°C-8°C). Avoid leaving your COPAXONE® in a hot or cold car.

When traveling with COPAXONE® or when you are not able to refrigerate, pre-filled syringes may be stored at room temperature between 59°F and 86°F (15°C-30°C), for up to 1 month. Discard after one month.

What happens if COPAXONE® freezes?1

Never freeze your COPAXONE® pre-filled syringes. If they do accidentally freeze, do not use, and dispose of your COPAXONE® in a proper container.

How do I dispose of COPAXONE® Pre-filled syringes?1

Remember to properly dispose of used syringes into a hard-walled container immediately after you inject for safe needle disposal. Consider using a needle clip device, available online and at many retail pharmacies, which snaps your used needle off the syringe and houses it in a small device that can hold hundreds of needles before requiring disposal. Check with your local health department, doctor's office, or pharmacist for guidance on how to follow local biohazard regulations for disposing of the needle clip device. Always keep your waste container in an area of your home that is out of the reach of children and pets.

COPAXONE® disposal of pre-filled syringes

How do I manage traveling with COPAXONE®?

For your free COPAXONE® Travel Kit, call Teva’s Shared Solutions® at 1-800-887-8100. Get started by downloading our Travel Planning Guide.

Packing

Stay prepared for unexpected changes in plans by keeping extra supplies on hand, including syringes, cotton balls and alcohol wipes, protected in sealed plastic bags. Avoid unnecessary delays by bringing your current prescription label with you; the label should match your name as it appears on your government-issued ID.

Flying

Keep your COPAXONE® pre-filled syringes and autoject®2 for glass syringe in your carry-on luggage, so they're easily available when going through airport security and safely in your possession if your luggage gets lost or damaged. Rest assured, your COPAXONE® should not be affected when passing through X-ray security measures at the airport. For current regulations, contact the Transportation Security Administration.

Use

COPAXONE® (glatiramer acetate injection) is prescription medicine used for the treatment of people with relapsing forms of multiple sclerosis (MS).

Important Safety Information

Do not take COPAXONE® if you are allergic to glatiramer acetate or mannitol.

Some patients report a short-term reaction right after or within minutes after injecting COPAXONE®. This reaction can involve flushing (feeling of warmth and/or redness), chest tightness or pain, fast heart beat, anxiety, and trouble breathing. These symptoms generally appear within seconds to minutes of an injection, last about 15 minutes, and do not require specific treatment. During the postmarketing period, there have been reports of patients with similar symptoms who received emergency medical care. If symptoms become severe, call the emergency phone number in your area. Call your doctor right away if you develop hives, skin rash with irritation, dizziness, sweating, chest pain, trouble breathing, or severe pain at the injection site. If any of the above occurs, do not give yourself any more injections until your doctor tells you to begin again.

Chest pain may occur either as part of the immediate post-injection reaction or on its own. This pain should only last a few minutes. You may experience more than one such episode, usually beginning at least one month after starting treatment. Tell your doctor if you experience chest pain that lasts for a long time or feels very intense.

A permanent indentation under the skin (lipoatrophy or, rarely, necrosis) at the injection site may occur, due to local destruction of fat tissue. Be sure to follow proper injection technique and inform your doctor of any skin changes.

The most common side effects of COPAXONE® include redness, pain, swelling, itching, or a lump at the site of injection, flushing, rash, shortness of breath, and chest pain. These are not all of the possible side effects of COPAXONE®. For a complete list, ask your doctor or pharmacist. Tell your doctor about any side effects you have while taking COPAXONE®.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Prescribing Information for Teva's COPAXONE®.

Reference: 1. COPAXONE® (glatiramer acetate injection) Current Prescribing Information. Teva Neuroscience, Inc.

Injections for 3-times-a-week COPAXONE® 40 mg must be at least 48 hours apart.

autoject®2 for glass syringe is a registered trademark of Owen Mumford, Ltd. Available by prescription only.
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