HERE WITH EMPOWERING FACTS ABOUT SIDE EFFECTS.

Knowing what to look for can help you manage your relapsing MS.1

HEAR HOW YOU CAN EMPOWER YOURSELF WITH FACTS ABOUT YOUR MS THERAPY, FROM AN MS SPECIALIST:

Side effects are possible, so here’s what you need to know.1

When using COPAXONE®, you may experience immediate post-injection reactions (serious side effects right after or within minutes of injecting COPAXONE®) or other side effects (which can happen at any time during the course of your treatment).

CALL YOUR DOCTOR RIGHT AWAY IF YOU EXPERIENCE ANY OF THESE IMMEDIATE POST-INJECTION REACTIONS FROM COPAXONE®1:

  • flushing (redness to your cheeks or other parts of the body)

  • chest pain

  • fast heart beat

  • anxiety

  • breathing problems or tightness in your throat

  • swelling, rash, hives, or itching

If you have symptoms of an immediate post-injection reaction, do not give yourself more injections until advised to do so by a doctor.

OTHER SERIOUS SIDE EFFECTS INCLUDE1:

  • chest pain (This can be as part of an immediate post-injection reaction or a symptom by itself; this type of chest pain usually lasts a few minutes and can begin around 1 month after starting COPAXONE® treatment. Call your doctor right away if you experience chest pain while using COPAXONE®).

  • damage to your skin (damage to the fatty tissue just under your skin's surface (lipoatrophy) and, rarely, death of your skin tissue (necrosis) can happen when you use COPAXONE®. Damage to the fatty tissue under your skin can cause a "dent" at the injection site that may not go away).

YOU CAN REDUCE YOUR CHANCE OF DEVELOPING DAMAGE TO YOUR SKIN BY:

  • following your doctor's instructions for how to use COPAXONE®

  • rotating injection areas each time you use COPAXONE®1

  • downloading our Skin Care Guide for techniques to help keep your skin healthy while injecting COPAXONE®

WHAT ARE THE MOST COMMON SIDE EFFECTS OF COPAXONE®?1

  • skin problems at the injection site (redness, pain, swelling, itching or lumps)

  • rash

  • shortness of breath

  • flushing (redness to your cheeks or other parts of the body)

These are not all the possible side effects of COPAXONE®.1 For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

WHAT IF I’M SWITCHING TO COPAXONE® FROM ANOTHER THERAPY?

Be sure to follow the advice of your doctor. It is highly recommended that you schedule a free, in-home, 1-on-1 injection training with a Teva’s Shared Solutions® nurse before starting COPAXONE®.

HOW DOES COPAXONE® INTERACT WITH OTHER MEDICATIONS?1

Although not fully studied, COPAXONE® has no known significant interactions with medications commonly used in MS patients. This includes concurrent use with corticosteroids (up to 28 days). COPAXONE® has not been formally evaluated in combination with interferon beta.

SHOULD I TAKE COPAXONE® IF I’M PREGNANT?1

Before you use COPAXONE®, tell your doctor if you are pregnant or plan to become pregnant. It is not known if COPAXONE® will harm your unborn baby. For more information, download our MS & Pregnancy brochure.

READY TO MANAGE YOUR INJECTIONS?

Turn to Teva’s Shared Solutions® for 1-on-1, nurse-led training when you begin COPAXONE®, including advice on how to help minimize injection site reactions.

Use

COPAXONE® is a prescription medicine that is used to treat relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, in adults.

Important Safety Information

Do not use COPAXONE® if you are allergic to glatiramer acetate or mannitol.

Serious side effects may happen right after or within minutes after you inject COPAXONE® at any time during your course of treatment. Call your doctor right away if you have any of these immediate post-injection reaction symptoms including: redness to your cheeks or other parts of the body (flushing); chest pain; fast heart beat; anxiety; breathing problems or tightness in your throat; or swelling, rash, hives, or itching. If you have symptoms of an immediate post-injection reaction, do not give yourself more injections until a doctor tells you to.

You can have chest pain as part of an immediate post-injection reaction or by itself. This type of chest pain usually lasts a few minutes and can begin around 1 month after you start using COPAXONE®. Call your doctor right away if you have chest pain while using COPAXONE®.

Damage to the fatty tissue just under your skin’s surface (lipoatrophy) and, rarely, death of your skin tissue (necrosis) can happen when you use COPAXONE®. Damage to the fatty tissue under your skin can cause a “dent” at the injection site that may not go away. You can reduce your chance of developing these problems by following your doctor’s instructions for how to use COPAXONE® and choosing a different injection area each time you use COPAXONE®.

The most common side effects of COPAXONE® include redness, pain, swelling, itching, or a lump at the injection site; rash; shortness of breath; flushing; and chest pain.

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of COPAXONE®. For more information, ask your doctor or pharmacist. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the Patient Information in the full Prescribing Information.

Reference: 1. COPAXONE® (glatiramer acetate injection) Current Prescribing Information. Teva Neuroscience, Inc.

Injections for 3-times-a-week COPAXONE® 40 mg must be at least 48 hours apart.

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